SyncleRef™
Reference Synthetic Vesicles
UNIFORM
Meticulously engineered for monodispersity (PDI < 0.05), while featuring a consistently hollow vesicle morphology.
STABLE
Room-temperature stable without any surfactants or additives. Tolerates salts and pH changes.
PRECISE
Multiple monodisperse sub-200 nm nominal sizes to choose from.
VERSATILE
Engineered for broad utility beyond calibration; useful as fluidic tracers, nanoplastics reference material, or as controls in vesicle-based assays.
CONSISTENT
Manufactured with strict quality control and low batch variability, and validated using multiple analyzers to ensure reproducible results.
Key Features & Real-World Data
01
Monodispersity Ensured
SyncleRef™ features a narrow
size distribution and an impressively low polydispersity index (PDI < 0.05).
Multiple Size Options
02
Our proprietary process enables SyncleRef™ to be produced with sub-200 nm precision.
Five nominal sizes are currently available: 65 nm, 105 nm, 120 nm, 135 nm, and 165 nm.
Additional sizes are currently in development.
Room Temperature Stability
03
Unlike traditional lipid-based vesicles, which typically require freezing for storage and gentle thawing prior to use, SyncleRef™ boasts room temperature stability over long periods of time.
Extensively Validated
04
All SyncleRef™ products are manufactured under rigorous quality control and characterized using various nanoparticle analyzers. Detailed technical specifications are provided in our product data sheet (PDS) and corresponding certificates of analysis (COA).
Low-magnification TEM image highlighting the uniformity of SyncleRef™ across a large field of view. Shown inset is a higher magnification, negatively stained image of the same sample.
(Left) Stacked particle size distribution showcasing the size difference of different SyncleRef™ products. (Right) Side-by-side electron microscopy comparison of SyncleRef™ 65 nm vs 165 nm.
Stability of SyncleRef™ 135 nm over 5 months of room temperature storage, as monitored by DLS.
Single-particle nano-flow cytometry data of SyncleRef™ 135 nm acquired on a Beckman Coulter Cytoflex Nano.
Nanoparticle tracking analysis (NTA) data of SyncleRef™ 135 nm acquired on a ParticleMetrix ZetaView® QUATT.
